Preferred Name

Ethynodiol Diacetate

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47525

CAS_Registry

297-76-7

CHEBI_ID

CHEBI:31580

Chemical_Formula

C24H32O4

code

C47525

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The diacetate salt form of ethynodiol, a semi-synthetic progestational hormone agonist. Ethynodiol diacetate binds to cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. As a result of the negative feedback mechanism, luteinizing hormone (LH) release is inhibited, which leads to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. In addition, ethynodiol diacetate has weak oestrogenic and androgenic properties.

FDA_UNII_Code

62H10A1236

FULL_SYN

(3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol Diacetate

Ethynodiol Diacetate

17-alpha-Ethynyl-19-norandrost-4-ene-3-beta,17-beta-diol Diacetate

ETHYNODIOL DIACETATE

label

Ethynodiol Diacetate

Legacy Concept Name

Ethynodiol_Diacetate

Preferred_Name

Ethynodiol Diacetate

prefixIRI

Thesaurus:C47525

prefLabel

Ethynodiol Diacetate

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0015117

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C776

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http://purl.obolibrary.org/obo/CHEBI_31580 Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体 LOOM
http://purl.bioontology.org/ontology/MESH/D005040 Medical Subject Headings / 医学主题词表 LOOM