loading...| Preferred Name |
apoptotic process |
| Synonyms |
apoptosis induction of apoptosis induction of apoptosis by p53 activation of apoptosis signaling (initiator) caspase activity apoptotic programmed cell death cell suicide programmed cell death by apoptosis apoptotic program commitment to apoptosis apoptosis signaling apoptotic cell death caspase-dependent programmed cell death cellular suicide type I programmed cell death apoptosis activator activity |
| Definitions |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| ID |
http://purl.obolibrary.org/obo/GO_0006915 |
| database_cross_reference |
Wikipedia:Apoptosis |
| has exact synonym |
apoptotic programmed cell death programmed cell death by apoptosis apoptotic cell death |
| has_alternative_id |
GO:0006917 GO:0008632 |
| has_broad_synonym |
cell suicide cellular suicide |
| has_narrow_synonym |
apoptosis activation of apoptosis apoptotic program apoptosis signaling type I programmed cell death |
| has_related_synonym |
induction of apoptosis induction of apoptosis by p53 signaling (initiator) caspase activity commitment to apoptosis caspase-dependent programmed cell death apoptosis activator activity |
| id |
GO:0006915 |
| label |
apoptotic process |
| notation |
GO:0006915 |
| prefixIRI |
GO:0006915 |
| prefLabel |
apoptotic process |
| RO_0002161 | |
| textual definition |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| 引自 | |
| 有_obo_命名空间 |
biological_process |
| subClassOf |