loading...| Preferred Name |
Alzheimer's disease |
| Synonyms |
Alzheimers dementia |
| Definitions |
Xref MGI. OMIM mapping confirmed by DO. [SN]. A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| ID |
http://purl.obolibrary.org/obo/DOID_10652 |
| comment |
Xref MGI. OMIM mapping confirmed by DO. [SN]. |
| database_cross_reference |
EFO:0000249 ICD10CM:G30 KEGG:05010 GARD:10254 ICD9CM:331.0 NCI:C2866 UMLS_CUI:C0002395 SNOMEDCT_US_2020_03_01:73768007 MESH:D000544 |
| has exact synonym |
Alzheimers dementia Alzheimer disease |
| id |
DOID:10652 |
| in_subset | |
| label |
Alzheimer's disease |
| notation |
DOID:10652 |
| prefLabel |
Alzheimer's disease |
| textual definition |
A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| 引自 | |
| 有_obo_命名空间 |
disease_ontology |
| subClassOf |