Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

blood brain barrier

Synonyms

blood-brain barrier

BBB

Definitions

Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions.

ID

http://purl.obolibrary.org/obo/UBERON_0000120

adjacent to

http://purl.obolibrary.org/obo/UBERON_0000179

http://purl.obolibrary.org/obo/UBERON_0000955

database_cross_reference

UMLS:C0005854

Wikipedia:Blood-brain_barrier

NCIT:C13194

MESH:D001812

http://uri.neuinfo.org/nif/nifstd/nlx_subcell_100205

definition

Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions.

has_exact_synonym

blood-brain barrier

has_obo_namespace

uberon

has_related_synonym

BBB

id

UBERON:0000120

label

blood brain barrier

notation

UBERON:0000120

part_of

http://purl.obolibrary.org/obo/UBERON_0001016

prefLabel

blood brain barrier

treeView

http://purl.obolibrary.org/obo/UBERON_0001016

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000119

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