Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

glomerular basement membrane

Synonyms

glomerular filtration membrane

glomerular capillary basement membrane

GBM

Definitions

The layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter.

ID

http://purl.obolibrary.org/obo/UBERON_0005777

capable of

http://purl.obolibrary.org/obo/GO_0003094

database_cross_reference

FMA:74274

MESH:D050533

UMLS:C0599297

Wikipedia:Glomerular_basement_membrane

MA:0001659

NCIT:C32683

EMAPA:30965

ZFA:0005285

EMAPA:28251

TAO:0005285

SCTID:243897006

definition

The layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter.

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png

has_broad_synonym

GBM

has_exact_synonym

glomerular filtration membrane

glomerular capillary basement membrane

has_obo_namespace

uberon

id

UBERON:0005777

in_subset

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

label

glomerular basement membrane

notation

UBERON:0005777

part_of

http://purl.obolibrary.org/obo/UBERON_0004188

prefLabel

glomerular basement membrane

treeView

http://purl.obolibrary.org/obo/UBERON_0004188

UBPROP_0000001

Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space.[TAO]

subClassOf

http://purl.obolibrary.org/obo/UBERON_0005769

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