| Preferred Name |
germinal center |
| Synonyms |
lymhpoid nodule light zone of follicle reaction center of follicle central zone of follice nodule |
| Definitions |
A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO] A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0010754 |
| comment |
A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO] |
| database_cross_reference |
NCIT:C13337 Wikipedia:Germinal_center MESH:D018858 SCTID:64626006 BTO:0003671 UMLS:C0282491 EV:0100051 |
| definition |
A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. |
| depicted by |
https://upload.wikimedia.org/wikipedia/commons/6/60/Germinal_center.svg |
| has_exact_synonym |
reaction center of follicle central zone of follice |
| has_narrow_synonym |
light zone of follicle |
| has_obo_namespace |
uberon |
| has_related_synonym |
lymhpoid nodule nodule |
| id |
UBERON:0010754 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
| label |
germinal center |
| notation |
UBERON:0010754 |
| part_of | |
| prefLabel |
germinal center |
| present_in_taxon | |
| treeView | |
| subClassOf |