Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

germinal center

Synonyms

lymhpoid nodule

light zone of follicle

reaction center of follicle

central zone of follice

nodule

Definitions

A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO] A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center.

ID

http://purl.obolibrary.org/obo/UBERON_0010754

comment

A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO]

database_cross_reference

NCIT:C13337

Wikipedia:Germinal_center

MESH:D018858

SCTID:64626006

BTO:0003671

UMLS:C0282491

EV:0100051

definition

A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center.

depicted by

https://upload.wikimedia.org/wikipedia/commons/6/60/Germinal_center.svg

has_exact_synonym

reaction center of follicle

central zone of follice

has_narrow_synonym

light zone of follicle

has_obo_namespace

uberon

has_related_synonym

lymhpoid nodule

nodule

id

UBERON:0010754

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

label

germinal center

notation

UBERON:0010754

part_of

http://purl.obolibrary.org/obo/UBERON_0001745

prefLabel

germinal center

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

treeView

http://purl.obolibrary.org/obo/UBERON_0001745

subClassOf

http://purl.obolibrary.org/obo/UBERON_0001744

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