loading...| Preferred Name |
pronephros |
| Synonyms |
archinephron pronephron embryonic kidney pronephric kidney |
| Definitions |
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0002120 |
| comment |
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 |
| database_cross_reference |
ZFA:0000151 UMLS:C0231048 AAO:0011089 SCTID:308804007 MESH:D060910 XAO:0002000 MIAA:0000117 FMA:72170 NCIT:C34280 Wikipedia:Pronephros EMAPA:16579 EHDAA:1017 EHDAA2:0001570 MAT:0000117 EFO:0000927 BTO:0001541 VHOG:0000037 TAO:0000151 |
| definition |
In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. |
| develops_from | |
| has_alternative_id |
UBERON:0005794 |
| has_exact_synonym |
pronephric kidney |
| has_obo_namespace |
uberon |
| has_related_synonym |
archinephron pronephron embryonic kidney |
| id |
UBERON:0002120 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim |
| label |
pronephros |
| located in | |
| notation |
UBERON:0002120 |
| prefLabel |
pronephros |
| treeView | |
| UBPROP_0000001 |
The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO] Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO] A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG] |
| UBPROP_0000003 |
In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG] |
| UBPROP_0000007 |
pronephric |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0002113 |