loading...| Preferred Name |
Orofacial cleft |
| Synonyms |
Cleft lip, cleft palate Cleft lip/palate Oral cleft Cleft of the mouth Oral clefting |
| Definitions |
The presence of a cleft in the oral cavity, the two main types of which are cleft lip and cleft palate. In cleft lip, there is the congenital failure of the maxillary and median nasal processes to fuse, forming a groove or fissure in the lip. In cleft palate, there is a congenital failure of the palate to fuse properly, forming a grooved depression or fissure in the roof of the mouth. Clefts of the lip and palate can occur individually or together. It is preferable to code each defect separately. |
| ID |
http://purl.obolibrary.org/obo/HP_0000202 |
| database_cross_reference |
UMLS:C0158646 ICD10:Q37 UMLS:C4021813 SNOMEDCT_US:66948001 SNOMEDCT_US:253983005 |
| definition |
The presence of a cleft in the oral cavity, the two main types of which are cleft lip and cleft palate. In cleft lip, there is the congenital failure of the maxillary and median nasal processes to fuse, forming a groove or fissure in the lip. In cleft palate, there is a congenital failure of the palate to fuse properly, forming a grooved depression or fissure in the roof of the mouth. Clefts of the lip and palate can occur individually or together. It is preferable to code each defect separately. |
| gwas_trait |
true |
| has_exact_synonym |
Oral cleft Cleft of the mouth Oral clefting |
| has_narrow_synonym |
Cleft lip, cleft palate |
| has_related_synonym |
Cleft lip/palate |
| id |
HP:0000202 |
| label |
Orofacial cleft |
| notation |
HP:0000202 |
| prefLabel |
Orofacial cleft |
| subClassOf |