loading...| Preferred Name |
myeloid suppressor cell |
| Definitions |
Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis. An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. |
| ID |
http://purl.obolibrary.org/obo/CL_0000889 |
| comment |
Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis. |
| definition |
An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. |
| in_subset |
http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim |
| label |
myeloid suppressor cell |
| prefixIRI |
obo2:CL_0000889 |
| prefLabel |
myeloid suppressor cell |
| subClassOf |