loading...| Preferred Name |
tuberculosis |
| Synonyms |
active tuberculosis tuberculosis disease |
| Definitions |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
| ID |
http://purl.obolibrary.org/obo/MONDO_0018076 |
| database_cross_reference |
Orphanet:3389 ICD9:017.96 MedDRA:10044755 ICD9:017.94 DOID:399 SCTID:56717001 UMLS:C0151332 ICD10CM:A15-A19 MESH:D014376 NCIT:C3423 GARD:0007827 ICD9:017.92 UMLS:C0041296 ICD9:017.90 |
| definition |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
| has exact synonym |
tuberculosis disease |
| has narrow synonym |
active tuberculosis |
| imported from | |
| inSubset |
http://purl.oboInOwllibrary.org/oboInOwl/mondo#rare http://purl.oboInOwllibrary.org/oboInOwl/mondo#ordo_disease http://purl.oboInOwllibrary.org/oboInOwl/mondo#orphanet_rare |
| label |
tuberculosis |
| prefixIRI |
MONDO:0018076 |
| prefLabel |
tuberculosis |
| subClassOf |