Gene Ontology / 基因本体

Last uploaded: August 7, 2023
Preferred Name

RNA N6-methyladenosine methyltransferase complex

Synonyms

m(6)A writer complex

WMM complex

MIS complex

METTL3-METTL14-WTAP methyltransferase complex

Mum2, Ime4, and Slz1 complex

m6A methyltransferase complex

Definitions

A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).

ID

http://purl.obolibrary.org/obo/GO_0036396

created_by

bf

creation_date

2013-07-15T10:17:50Z

definition

A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).

has_exact_synonym

WMM complex

Mum2, Ime4, and Slz1 complex

has_obo_namespace

cellular_component

has_related_synonym

m(6)A writer complex

MIS complex

METTL3-METTL14-WTAP methyltransferase complex

m6A methyltransferase complex

id

GO:0036396

label

RNA N6-methyladenosine methyltransferase complex

notation

GO:0036396

prefLabel

RNA N6-methyladenosine methyltransferase complex

treeView

http://purl.obolibrary.org/obo/GO_0045293

http://purl.obolibrary.org/obo/GO_0034708

subClassOf

http://purl.obolibrary.org/obo/GO_0045293

http://purl.obolibrary.org/obo/GO_0034708

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