| Preferred Name |
RNA N6-methyladenosine methyltransferase complex |
| Synonyms |
m(6)A writer complex WMM complex MIS complex METTL3-METTL14-WTAP methyltransferase complex Mum2, Ime4, and Slz1 complex m6A methyltransferase complex |
| Definitions |
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). |
| ID |
http://purl.obolibrary.org/obo/GO_0036396 |
| created_by |
bf |
| creation_date |
2013-07-15T10:17:50Z |
| definition |
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). |
| has_exact_synonym |
WMM complex Mum2, Ime4, and Slz1 complex |
| has_obo_namespace |
cellular_component |
| has_related_synonym |
m(6)A writer complex MIS complex METTL3-METTL14-WTAP methyltransferase complex m6A methyltransferase complex |
| id |
GO:0036396 |
| label |
RNA N6-methyladenosine methyltransferase complex |
| notation |
GO:0036396 |
| prefLabel |
RNA N6-methyladenosine methyltransferase complex |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||