loading...| Preferred Name |
exosome (RNase complex) |
| Synonyms |
exosome multienzyme ribonuclease complex exosome (ribonucleasease complex) |
| Definitions |
Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies. A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. |
| ID |
http://purl.obolibrary.org/obo/GO_0000178 |
| comment |
Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies. |
| definition |
A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. |
| has_exact_synonym |
exosome multienzyme ribonuclease complex exosome (ribonucleasease complex) |
| has_obo_namespace |
cellular_component |
| id |
GO:0000178 |
| in_subset | |
| label |
exosome (RNase complex) |
| notation |
GO:0000178 |
| part_of | |
| prefLabel |
exosome (RNase complex) |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||