Human Phenotype Ontology / 人类表型本体

Last uploaded: September 7, 2023
Preferred Name

Premature adrenarche

Definitions

Adrenarche is an early sexual maturation stage that typically occurs at around 6 to 8 years of age, during which the adrenal cortex begins to secrete increased levels of androgens resulting from the development of the zona reticularis in the adrenal cortex. Note that pubarche refers to the development of pubic hair, axillary hair, and adult sweat gland (apocrine) odor. The physical features associated with pubarche reflect the onset of adrenarche, which refers to the pubertal maturation of the adrenal and is associated with increased secretion of an adrenal hormone called dehydroepiandrosterone sulfate (DHEAS). Onset of adrenarche at an earlier age than usual.

ID

http://purl.obolibrary.org/obo/HP_0012412

comment

Adrenarche is an early sexual maturation stage that typically occurs at around 6 to 8 years of age, during which the adrenal cortex begins to secrete increased levels of androgens resulting from the development of the zona reticularis in the adrenal cortex. Note that pubarche refers to the development of pubic hair, axillary hair, and adult sweat gland (apocrine) odor. The physical features associated with pubarche reflect the onset of adrenarche, which refers to the pubertal maturation of the adrenal and is associated with increased secretion of an adrenal hormone called dehydroepiandrosterone sulfate (DHEAS).

creation_date

2013-11-10T11:58:02Z

creator

https://orcid.org/0000-0002-0736-9199

database_cross_reference

SNOMEDCT_US:103021001

UMLS:C0342546

definition

Onset of adrenarche at an earlier age than usual.

has_obo_namespace

human_phenotype

id

HP:0012412

label

Premature adrenarche

notation

HP:0012412

prefLabel

Premature adrenarche

treeView

http://purl.obolibrary.org/obo/HP_0100000

subClassOf

http://purl.obolibrary.org/obo/HP_0100000

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113337 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU037066 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/5A76.0 《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China LOOM