Preferred Name

interleukin-10

Synonyms

CSIF

IL-10

cytokine synthesis inhibitory factor

IL10

Definitions

A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds. Category=gene.

ID

http://purl.obolibrary.org/obo/PR_000001471

comment

Category=gene.

database_cross_reference

PANTHER:PTHR11585:SF1

definition

A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds.

has_exact_synonym

CSIF

IL-10

cytokine synthesis inhibitory factor

IL10

has_obo_namespace

protein

id

PR:000001471

label

interleukin-10

notation

PR:000001471

prefLabel

interleukin-10

subClassOf

http://purl.obolibrary.org/obo/PR_000001335

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http://purl.obolibrary.org/obo/PR_000001471 Protein Ontology / 蛋白质本体 LOOM
http://purl.obolibrary.org/obo/PR_000001471 Protein Ontology / 蛋白质本体 SAME_URI
http://purl.obolibrary.org/obo/PR_000001471 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) / 国家实验细胞资源共享服务平台(NICR)细胞系本体子集 LOOM
http://purl.obolibrary.org/obo/PR_000001471 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) / 国家实验细胞资源共享服务平台(NICR)细胞系本体子集 SAME_URI
http://purl.org/sig/ont/fma/fma264825 Foundational Model of Anatomy / 解剖学基础模型本体 LOOM
http://purl.bioontology.org/ontology/MESH/D016753 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/LNC/LP21163-8 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM
http://purl.bioontology.org/ontology/LNC/MTHU012952 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 LOOM
http://purl.bioontology.org/ontology/OMIM/124092 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20512 National Cancer Institute Thesaurus / 美国国家癌症研究所词典 LOOM
http://www.orpha.net/ORDO/Orphanet_122623 Orphanet Rare Disease Ontology / Orphanet罕见病本体 LOOM