Preferred Name

Underactive Thyroid

Synonyms

Hypothyroidism

Definitions

<h3>What is hypothyroidism?</h3> <p>Hypothyroidism, or underactive thyroid, happens when your thyroid gland doesn't make enough thyroid hormones to meet your body's needs.</p> <p>Your <a href="https://medlineplus.gov/thyroiddiseases.html">thyroid</a> is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods. Without enough thyroid hormones, many of your body's functions slow down. But there are treatments that can help.</p> <h3>What causes hypothyroidism?</h3> <p>Hypothyroidism has several causes. They include:</p><ul> <li>Hashimoto's disease, an autoimmune disorder where your immune system attacks your thyroid. This is the most common cause.</li> <li>Thyroiditis, inflammation of the thyroid</li> <li>Congenital hypothyroidism, hypothyroidism that is present at birth</li> <li>Surgical removal of part or all of the thyroid</li> <li><a href="https://medlineplus.gov/radiationtherapy.html">Radiation treatment</a> of the thyroid</li> <li>Certain medicines</li> <li>In rare cases, a <a href="https://medlineplus.gov/pituitarydisorders.html">pituitary disease</a> or too much or too little iodine in your diet</li> </ul> <h3>Who is at risk for hypothyroidism?</h3> <p>You are at higher risk for hypothyroidism if you:</p><ul> <li>Are a woman</li> <li>Are older than age 60</li> <li>Have had a thyroid problem before, such as a goiter</li> <li>Have had surgery to correct a thyroid problem</li> <li>Have received radiation treatment to the thyroid, neck, or chest</li> <li>Have a family history of thyroid disease</li> <li>Were pregnant or had a baby in the past 6 months</li> <li>Have <a href="https://medlineplus.gov/turnersyndrome.html">Turner syndrome</a>, a genetic disorder that affects females</li> <li>Have pernicious <a href="https://medlineplus.gov/anemia.html">anemia</a>, in which the body cannot make enough healthy red blood cells because it does not have enough <a href="https://medlineplus.gov/bvitamins.html">vitamin B12</a></li> <li>Have <a href="https://medlineplus.gov/sjogrenssyndrome.html">Sjogren's syndrome</a>, a disease that causes dry eyes and mouth</li> <li>Have <a href="https://medlineplus.gov/diabetestype1.html">type 1 diabetes</a></li> <li>Have <a href="https://medlineplus.gov/rheumatoidarthritis.html">rheumatoid arthritis</a>, an autoimmune disease that affects the joints</li> <li>Have <a href="https://medlineplus.gov/lupus.html">lupus</a>, a chronic autoimmune disease</li> </ul> <h3>What are the symptoms of hypothyroidism?</h3> <p>The symptoms of hypothyroidism can vary from person to person and may include:</p><ul> <li><a href="https://medlineplus.gov/fatigue.html">Fatigue</a></li> <li>Weight gain</li> <li>A puffy face</li> <li>Trouble tolerating cold</li> <li>Joint and muscle pain</li> <li><a href="https://medlineplus.gov/constipation.html">Constipation</a></li> <li>Dry skin</li> <li>Dry, thinning hair</li> <li>Decreased sweating</li> <li>Heavy or irregular <a href="https://medlineplus.gov/menstruation.html">menstrual periods</a></li> <li><a href="https://medlineplus.gov/femaleinfertility.html">Fertility problems in women</a></li> <li><a href="https://medlineplus.gov/depression.html">Depression</a></li> <li>Slowed heart rate</li> <li>Goiter, an enlarged thyroid that may cause your neck to look swollen. Sometimes it can cause trouble with breathing or swallowing.</li> </ul> <p>Because hypothyroidism develops slowly, many people don't notice symptoms of the disease for months or even years.</p> <h3>What other problems can hypothyroidism cause?</h3> <p>Hypothyroidism can contribute to <a href="https://medlineplus.gov/cholesterol.html">high cholesterol</a>. In rare cases, untreated hypothyroidism can cause myxedema coma. This is a condition in which your body's functions slow down to the point that it becomes life-threatening.</p> <p>During pregnancy, hypothyroidism can cause <a href="https://medlineplus.gov/healthproblemsinpregnancy.html">complications</a>, such as <a href="https://medlineplus.gov/pretermlabor.html">premature birth</a>, <a href="https://medlineplus.gov/highbloodpressureinpregnancy.html">high blood pressure in pregnancy</a>, and <a href="https://medlineplus.gov/miscarriage.html">miscarriage</a>. It can also slow the baby's <a href="https://medlineplus.gov/fetalhealthanddevelopment.html">growth and development</a>.</p> <h3>How is hypothyroidism diagnosed?</h3> <p>Your health care provider may use many tools to make a diagnosis:</p><ul> <li>A medical history, including asking about your symptoms</li> <li>A physical exam</li> <li><a href="https://medlineplus.gov/thyroidtests.html">Thyroid tests</a>, such as <ul> <li><a href="https://medlineplus.gov/lab-tests/tsh-thyroid-stimulating-hormone-test/">TSH</a>, <a href="https://medlineplus.gov/lab-tests/triiodothyronine-t3-tests/">T3</a>, <a href="https://medlineplus.gov/lab-tests/thyroxine-t4-test/">T4</a>, and <a href="https://medlineplus.gov/lab-tests/thyroid-antibodies/">thyroid antibody blood tests</a></li> <li><a href="https://medlineplus.gov/diagnosticimaging.html">Imaging tests</a>, such as a thyroid scan, <a href="https://medlineplus.gov/lab-tests/sonogram/">ultrasound</a>, or radioactive iodine uptake test. A radioactive iodine uptake test measures how much radioactive iodine your thyroid takes up from your blood after you swallow a small amount of it.</li> </ul> </li> </ul> <h3>What are the treatments for hypothyroidism?</h3> <p>The treatment for hypothyroidism is medicine to replace the hormone that your own thyroid can no longer make. About 6 to 8 weeks after you start taking the medicine, you will get a blood test to check your thyroid hormone level. Your health care provider will adjust your dose if needed. Each time your dose is adjusted, you'll have another blood test. Once you find the right dose, you will probably get a blood test in 6 months. After that, you will need the test once a year.</p> <p>If you take your medicine according to the instructions, you usually should be able to control the hypothyroidism. You should never stop taking your medicine without talking with your health care provider first.</p> <p>If you have Hashimoto's disease or other types of autoimmune thyroid disorders, you may be sensitive to harmful side effects from iodine. Talk to your health care provider about which foods, supplements, and medicines you need to avoid.</p> <p>Women need more iodine when they are pregnant because the baby gets iodine from the mother's diet. If you are pregnant, talk with your health care provider about how much iodine you need.</p> <p class="">NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020676

altLabel

Hypothyroidism

Underactive thyroid

cui

C0020676

Date created

12/23/2013

definition

What is hypothyroidism?

Hypothyroidism, or underactive thyroid, happens when your thyroid gland doesn't make enough thyroid hormones to meet your body's needs.

Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods. Without enough thyroid hormones, many of your body's functions slow down. But there are treatments that can help.

What causes hypothyroidism?

Hypothyroidism has several causes. They include:

  • Hashimoto's disease, an autoimmune disorder where your immune system attacks your thyroid. This is the most common cause.
  • Thyroiditis, inflammation of the thyroid
  • Congenital hypothyroidism, hypothyroidism that is present at birth
  • Surgical removal of part or all of the thyroid
  • Radiation treatment of the thyroid
  • Certain medicines
  • In rare cases, a pituitary disease or too much or too little iodine in your diet

Who is at risk for hypothyroidism?

You are at higher risk for hypothyroidism if you:

  • Are a woman
  • Are older than age 60
  • Have had a thyroid problem before, such as a goiter
  • Have had surgery to correct a thyroid problem
  • Have received radiation treatment to the thyroid, neck, or chest
  • Have a family history of thyroid disease
  • Were pregnant or had a baby in the past 6 months
  • Have Turner syndrome, a genetic disorder that affects females
  • Have pernicious anemia, in which the body cannot make enough healthy red blood cells because it does not have enough vitamin B12
  • Have Sjogren's syndrome, a disease that causes dry eyes and mouth
  • Have type 1 diabetes
  • Have rheumatoid arthritis, an autoimmune disease that affects the joints
  • Have lupus, a chronic autoimmune disease

What are the symptoms of hypothyroidism?

The symptoms of hypothyroidism can vary from person to person and may include:

  • Fatigue
  • Weight gain
  • A puffy face
  • Trouble tolerating cold
  • Joint and muscle pain
  • Constipation
  • Dry skin
  • Dry, thinning hair
  • Decreased sweating
  • Heavy or irregular menstrual periods
  • Fertility problems in women
  • Depression
  • Slowed heart rate
  • Goiter, an enlarged thyroid that may cause your neck to look swollen. Sometimes it can cause trouble with breathing or swallowing.

Because hypothyroidism develops slowly, many people don't notice symptoms of the disease for months or even years.

What other problems can hypothyroidism cause?

Hypothyroidism can contribute to high cholesterol. In rare cases, untreated hypothyroidism can cause myxedema coma. This is a condition in which your body's functions slow down to the point that it becomes life-threatening.

During pregnancy, hypothyroidism can cause complications, such as premature birth, high blood pressure in pregnancy, and miscarriage. It can also slow the baby's growth and development.

How is hypothyroidism diagnosed?

Your health care provider may use many tools to make a diagnosis:

  • A medical history, including asking about your symptoms
  • A physical exam
  • Thyroid tests, such as

What are the treatments for hypothyroidism?

The treatment for hypothyroidism is medicine to replace the hormone that your own thyroid can no longer make. About 6 to 8 weeks after you start taking the medicine, you will get a blood test to check your thyroid hormone level. Your health care provider will adjust your dose if needed. Each time your dose is adjusted, you'll have another blood test. Once you find the right dose, you will probably get a blood test in 6 months. After that, you will need the test once a year.

If you take your medicine according to the instructions, you usually should be able to control the hypothyroidism. You should never stop taking your medicine without talking with your health care provider first.

If you have Hashimoto's disease or other types of autoimmune thyroid disorders, you may be sensitive to harmful side effects from iodine. Talk to your health care provider about which foods, supplements, and medicines you need to avoid.

Women need more iodine when they are pregnant because the baby gets iodine from the mother's diet. If you are pregnant, talk with your health care provider about how much iodine you need.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0677607

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020676

Inverse of SY

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020676

Mapped from

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020676

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020676

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/hypothyroidism.html

MP PRIMARY INSTITUTE URL

National Institute of Diabetes and Digestive and Kidney Diseases https://www.niddk.nih.gov

notation

C0020676

prefLabel

Underactive Thyroid

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0040130

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0549473

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0040128

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0020550

Scope Statement

Hypothyroidism happens when your thyroid gland does not make enough thyroid hormone to meet your body's needs. Hypothyroidism is more common in women.https://medlineplus.gov/hypothyroidism.html

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0014136

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http://purl.bioontology.org/ontology/ICD10/E03.9 International Classification of Diseases, Version 10 / 《国际疾病分类》第10版 CUI
http://purl.bioontology.org/ontology/LNC/LP74946-2 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU002670 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/LNC/MTHU020783 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 CUI
http://purl.bioontology.org/ontology/LNC/LA14303-4 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 CUI
http://purl.bioontology.org/ontology/ICD10CM/E03.9 International Classification of Diseases, Version 10 - Clinical Modification / 国际疾病分类,第10版-临床修改 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU025716 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bmicc.cn/ontology/ICD10CN/E03.9 《国际疾病分类》第10版中文版 / International Classification of Diseases, 10th Edition, China CUI
http://purl.bioontology.org/ontology/MESH/D007037 Medical Subject Headings / 医学主题词表 CUI