loading...| Preferred Name |
Richardson-Steele-Olszewski syndrome |
| Synonyms |
Progressive Supranuclear Palsy |
| Definitions |
<h3>What is progressive supranuclear palsy (PSP)?</h3> <p>Progressive supranuclear palsy (PSP) is a rare <a href="https://medlineplus.gov/braindiseases.html">brain disease</a>. It happens because of damage to nerve cells in the brain. PSP affects your <a href="https://medlineplus.gov/movementdisorders.html">movement</a>, including control of your <a href="https://medlineplus.gov/walkingproblems.html">walking</a> and <a href="https://medlineplus.gov/balanceproblems.html">balance</a>. It also affects your thinking and <a href="https://medlineplus.gov/eyemovementdisorders.html">eye movement</a>.</p> <p>PSP is progressive, which means that it gets worse over time.</p> <h3>What causes progressive supranuclear palsy (PSP)?</h3> <p>The cause of PSP is unknown. In rare cases, the cause is a mutation in a certain gene.</p> <p>One sign of PSP is abnormal clumps of tau in nerve cells in the brain. Tau is a protein in your nervous system, including in nerve cells. Some other diseases also cause a buildup of tau in the brain, including <a href="https://medlineplus.gov/alzheimersdisease.html">Alzheimer's disease</a>.</p> <h3>Who is at risk for progressive supranuclear palsy (PSP)?</h3> <p>PSP usually affects people over 60, but in some cases it can start earlier. It is more common in men.</p> <h3>What are the symptoms of progressive supranuclear palsy (PSP)?</h3> <p>Symptoms are very different in each person, but they may include:</p><ul> <li>A loss of balance while walking. This is often the first symptom.</li> <li><a href="https://medlineplus.gov/speechandcommunicationdisorders.html">Speech problems</a></li> <li><a href="https://medlineplus.gov/swallowingdisorders.html">Trouble swallowing</a></li> <li>A <a href="https://medlineplus.gov/visionimpairmentandblindness.html">blurring of vision</a> and problems controlling eye movement</li> <li>Changes in mood and behavior, including <a href="https://medlineplus.gov/depression.html">depression</a> and apathy (a loss of interest and enthusiasm)</li> <li>Mild <a href="https://medlineplus.gov/dementia.html">dementia</a></li> </ul> <h3>How is progressive supranuclear palsy (PSP0 diagnosed?</h3> <p>There is no specific test for PSP. It can be difficult to diagnose, because the symptoms are similar to other diseases such as <a href="https://medlineplus.gov/parkinsonsdisease.html">Parkinson's disease</a> and Alzheimer's disease.</p> <p>To make a diagnosis, your health care provider will take your medical history and do physical and neurological exams. You may have an <a href="https://medlineplus.gov/mriscans.html">MRI</a> or other imaging tests.</p> <h3>What are the treatments for progressive supranuclear palsy (PSP)?</h3> <p>There is currently no effective treatment for PSP. Medicines may reduce some symptoms. Some non-drug treatments, such as walking aids and special glasses, may also help. People with severe swallowing problems may need gastrostomy. This is a surgery to insert a feeding tube into the stomach.</p> <p>PSP gets worse over time. Many people become severely disabled within three to five years after getting it. PSP isn't life-threatening on its own. It can still be be dangerous, because it increases your risk of <a href="https://medlineplus.gov/pneumonia.html">pneumonia</a>, choking from swallowing problems, and injuries from <a href="https://medlineplus.gov/falls.html">falling</a>. But with good attention to medical and nutritional needs, many people with PSP can live 10 or more years after the first symptoms of the disease.</p> <p class="">NIH: National Institute of Neurological Disorders and Stroke</p> |
| ID |
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0038868 |
| altLabel |
Progressive Supranuclear Palsy Steele-Richardson-Olszewski Syndrome Steele-Richardson-Olszewski syndrome PSP |
| cui |
C0038868 |
| Date created |
09/30/2003 |
| definition |
What is progressive supranuclear palsy (PSP)?Progressive supranuclear palsy (PSP) is a rare brain disease. It happens because of damage to nerve cells in the brain. PSP affects your movement, including control of your walking and balance. It also affects your thinking and eye movement. PSP is progressive, which means that it gets worse over time. What causes progressive supranuclear palsy (PSP)?The cause of PSP is unknown. In rare cases, the cause is a mutation in a certain gene. One sign of PSP is abnormal clumps of tau in nerve cells in the brain. Tau is a protein in your nervous system, including in nerve cells. Some other diseases also cause a buildup of tau in the brain, including Alzheimer's disease. Who is at risk for progressive supranuclear palsy (PSP)?PSP usually affects people over 60, but in some cases it can start earlier. It is more common in men. What are the symptoms of progressive supranuclear palsy (PSP)?Symptoms are very different in each person, but they may include:
How is progressive supranuclear palsy (PSP0 diagnosed?There is no specific test for PSP. It can be difficult to diagnose, because the symptoms are similar to other diseases such as Parkinson's disease and Alzheimer's disease. To make a diagnosis, your health care provider will take your medical history and do physical and neurological exams. You may have an MRI or other imaging tests. What are the treatments for progressive supranuclear palsy (PSP)?There is currently no effective treatment for PSP. Medicines may reduce some symptoms. Some non-drug treatments, such as walking aids and special glasses, may also help. People with severe swallowing problems may need gastrostomy. This is a surgery to insert a feeding tube into the stomach. PSP gets worse over time. Many people become severely disabled within three to five years after getting it. PSP isn't life-threatening on its own. It can still be be dangerous, because it increases your risk of pneumonia, choking from swallowing problems, and injuries from falling. But with good attention to medical and nutritional needs, many people with PSP can live 10 or more years after the first symptoms of the disease. NIH: National Institute of Neurological Disorders and Stroke |
| Inverse of RQ | |
| Inverse of SY | |
| Mapped from | |
| Mapped to | |
| MP OTHER LANGUAGE URL |
Spanish https://medlineplus.gov/spanish/progressivesupranuclearpalsy.html |
| MP PRIMARY INSTITUTE URL |
National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ |
| notation |
C0038868 |
| prefLabel |
Richardson-Steele-Olszewski syndrome |
| Related to | |
| Scope Statement |
Progressive supranuclear palsy (PSP) is a rare brain disease. It causes problems with balance, eye movement, and walking. Learn about what can help.https://medlineplus.gov/progressivesupranuclearpalsy.html |
| tui |
T047 |
| subClassOf |