loading...| Preferred Name |
Lymphocyte Activation |
| Synonyms |
Blast Transformation |
| Definitions |
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. |
| ID |
http://purl.bioontology.org/ontology/MESH/D008213 |
| altLabel |
Blast Transformation Blastogenesis Transformation, Blast Lymphocyte Stimulation Transformation, Lymphoblast Lymphocyte Transformation Stimulation, Lymphocyte Transformation, Lymphocyte Activation, Lymphocyte Lymphoblast Transformation |
| AN |
lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( = CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( = CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS |
| AQL |
DE GE IM PH RE |
| cui |
C0024262 |
| DC |
1 |
| definition |
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. |
| DX |
19720101 |
| FX |
D001752 |
| HN |
2003 (1969); for BLAST TRANSFORMATION use BLAST CRISIS 1987-1992 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D000938 |
| Machine permutation |
2003; see LYMPHOCYTE TRANSFORMATION 1972-2002; for BLAST TRANSFORMATION see BLAST CRISIS 1987-1992 |
| MDA |
19990101 |
| MMR |
20190524 |
| MN |
G12.450.050.400.545 G12.565 E05.478.594.530 E05.200.812.482 E01.370.225.812.482 |
| notation |
D008213 |
| prefLabel |
Lymphocyte Activation |
| TERMUI |
T024462 T024468 T024470 T024467 T024466 T024465 T024464 T024469 T024463 |
| TH |
NLM (1993) UNK (19XX) NLM (1990) NLM (1995) NLM (1969) |
| tui |
T043 |
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D055633 |