loading...| Preferred Name |
Isaacs Syndrome |
| Synonyms |
Isaacs' Syndrome |
| Definitions |
A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491) |
| ID |
http://purl.bioontology.org/ontology/MESH/D020386 |
| altLabel |
Isaacs' Syndrome Isaac Syndrome Isaacs-Mertens Syndrome Continuous Myokymias Isaacs Mertens Syndrome Pseudomyotonia Myokymias, Continuous Pseudomyotonia Syndrome of Isaacs Quantal Squander Isaacs Pseudomyotonia Syndrome Acquired Neuromyotonia Continuous Myokymia Continuous Muscle Activity Syndrome Myokymia, Myotonia, Muscle Wasting, And Hyperhidrosis Gamstorp Wohlfart Syndrome Neuromyotonia, Acquired Gamstorp-Wohlfart Syndrome Syndrome of Continuous Muscle Activity Myokymia, Continuous Neuromyotonia |
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
| cui |
C0751919 C4521481 C0242287 |
| DC |
1 |
| definition |
A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491) |
| DX |
20000101 |
| HN |
2000; for ISAACS' SYNDROME use FASCICULATION 1995-1999 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Machine permutation |
2000; for ISAACS' SYNDROME see FASCICULATION 1995-1999 |
| MDA |
19991103 |
| MMR |
20190517 |
| MN |
C05.651.392 C10.668.829.425 |
| notation |
D020386 |
| prefLabel |
Isaacs Syndrome |
| TERMUI |
T369955 T358686 T369956 T369954 T015973 T812143 T369953 T015972 T369952 T369958 T369959 T369951 T369957 |
| TH |
NLM (2000) NLM (1995) OMIM (2013) |
| tui |
T047 |
| subClassOf |