loading...| Preferred Name |
Hemoglobinuria, Paroxysmal |
| Synonyms |
Hemoglobinuria, Paroxysmal Cold |
| Definitions |
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins. |
| ID |
http://purl.bioontology.org/ontology/MESH/D006457 |
| altLabel |
Hemoglobinuria, Paroxysmal Cold Paroxysmal Cold Hemoglobinuria Marchiafava-Micheli Syndrome Paroxysmal Hemoglobinuria, Cold Syndrome, Marchiafava-Micheli Paroxysmal Hemoglobinuria, Nocturnal Hemoglobinuria, Paroxysmal Nocturnal Cold Paroxysmal Hemoglobinuria Hemoglobinuria, Nocturnal Paroxysmal Paroxysmal Hemoglobinuria Hemoglobinuria, Cold Paroxysmal Marchiafava Micheli Syndrome Paroxysmal Nocturnal Hemoglobinuria Nocturnal Paroxysmal Hemoglobinuria |
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
| cui |
C0019050 C0024790 C0086774 |
| DC |
1 |
| definition |
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins. |
| DX |
19780101 |
| HN |
78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Machine permutation |
78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77 |
| MDA |
19990101 |
| MMR |
20130708 |
| MN |
C15.378.190.625.460 C15.378.071.141.560 |
| notation |
D006457 |
| OL |
use HEMOGLOBINURIA, PAROXYSMAL to search MARCHIAFAVA-MICHELI SYNDROME 1966-77 |
| prefLabel |
Hemoglobinuria, Paroxysmal |
| TERMUI |
T019495 T666934 T019494 T019496 T666933 T019497 T666932 |
| TH |
UNK (19XX) NLM (1992) NLM (1966) NLM (2007) ORD (2010) OMIM (2013) GHR (2014) |
| tui |
T047 |
| subClassOf |