loading...| Preferred Name |
Staurosporine |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1237 |
| ALT_DEFINITION |
A drug that belongs to the family of drugs called alkaloids. It is being studied in the treatment of cancer. |
| CAS_Registry |
62996-74-1 |
| CHEBI_ID |
CHEBI:15738 |
| Chemical_Formula |
C28H26N4O3 |
| code |
C1237 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 |
| Contributing_Source |
GDC FDA |
| DEFINITION |
A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI) |
| FDA_UNII_Code |
H88EPA0A3N |
| FULL_SYN |
Antibiotic AM 2282 staurosporine Staurosporine Antibiotic 230 AM-2282 CGP-39360 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)- (9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one STAUROSPORINE |
| Is_Value_For_GDC_Property | |
| label |
Staurosporine |
| Legacy Concept Name |
Staurosporine |
| Maps_To |
Staurosporine |
| NSC Number |
618487 |
| Preferred_Name |
Staurosporine |
| prefixIRI |
Thesaurus:C1237 |
| prefLabel |
Staurosporine |
| Semantic_Type |
Pharmacologic Substance Organic Chemical |
| UMLS_CUI |
C0075193 |
| subClassOf |