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loading...| Preferred Name |
Endothelin-1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1285 |
| code |
C1285 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
| Contributing_Source |
CTRP |
| DEFINITION |
Endothelin-1 (212 aa, ~24 kDa) is encoded by the human EDN1 gene. This protein is involved in vasoconstriction. |
| DesignNote |
Endothelin-1 is proteolytically processed to form big endothelin-1 (38 amino acids) or a 21 amino acid peptide also called endothelin-1. The active forms inhibits active Na-K transport by inhibiting Na(+)-K(+)-ATPase in intact renaltubular epithelial cells. |
| Display_Name |
Endothelin-1 |
| FULL_SYN |
PPET1 ET-1 EDN1 Preproendothelin-1 Endothelin-1 Preproendothelin 1 Endothelin 1 |
| label |
Endothelin-1 |
| Legacy Concept Name |
Endothelin-1 |
| OMIM_Number |
131240 |
| Preferred_Name |
Endothelin-1 |
| prefixIRI |
Thesaurus:C1285 |
| prefLabel |
Endothelin-1 |
| Semantic_Type |
Hormone Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P05305 |
| UMLS_CUI |
C0079281 |
| subClassOf |
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