Preferred Name

Cadherin

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16373

code

C16373

DEFINITION

The cadherins are transmembrane glycoproteins involved in calcium dependent specific cell-cell adhesion through homophilic binding. They are crucial for morphogenesis and synapse formation, but also are involved in tumor invasion. The classical cadherins have five homologous extracellular domains and a cytosolic domain which binds through catenin to the cytoskeleton. The extracellular domains are immunoglobulin-like beta-sandwiches comprising usually 7 strands in the two sheets.

FULL_SYN

Cadherin

label

Cadherin

Legacy Concept Name

Cadherin

Preferred_Name

Cadherin

prefixIRI

Thesaurus:C16373

prefLabel

Cadherin

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0006631

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16393

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/PR_000001327 Protein Ontology / 蛋白质本体 LOOM
http://purl.obolibrary.org/obo/PR_000001327 Phenotypic Quality Ontology / 表型特质本体 LOOM
http://purl.obolibrary.org/obo/PR_000001327 Uber Anatomy Ontology / 超级解剖学本体 LOOM
http://purl.obolibrary.org/obo/PR_000001327 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) / 国家实验细胞资源共享服务平台(NICR)细胞系本体子集 LOOM
http://purl.obolibrary.org/obo/PR_000001327 Cell Ontology / 细胞本体 LOOM
http://purl.org/sig/ont/fma/fma61790 Foundational Model of Anatomy / 解剖学基础模型本体 LOOM