Preferred Name |
Luteinizing Hormone |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190789 |
code |
C190789 |
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
Contributing_Source |
CTRP |
DEFINITION |
A heterodimeric glycoprotein hormone secreted by the gonadotropic cells of the anterior pituitary gland. This hormone is involved in stimulation of testosterone production by Leydig cells in males and triggering ovulation and corpus luteum development in females. |
DesignNote |
Luteinizing hormone is comprised of an alpha chain, glycoprotein hormones alpha chain (CGA), which is the common alpha chain shared with LH, TSH, and hCG, and a unique beta chain, lutropin subunit beta (LHB), which confers specific binding to lutropin-choriogonadotropic hormone receptor (LHCGR). |
Display_Name |
Luteinizing Hormone |
FULL_SYN |
LH Interstitial Cell-Stimulating Hormone ICSH Luteinizing Hormone Lutropin |
label |
Luteinizing Hormone |
NCI_META_CUI |
CL1799696 |
Preferred_Name |
Luteinizing Hormone |
prefixIRI |
Thesaurus:C190789 |
prefLabel |
Luteinizing Hormone |
Semantic_Type |
Hormone Amino Acid, Peptide, or Protein |
subClassOf |