Preferred Name

Luteinizing Hormone

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C190789

code

C190789

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

Contributing_Source

CTRP

DEFINITION

A heterodimeric glycoprotein hormone secreted by the gonadotropic cells of the anterior pituitary gland. This hormone is involved in stimulation of testosterone production by Leydig cells in males and triggering ovulation and corpus luteum development in females.

DesignNote

Luteinizing hormone is comprised of an alpha chain, glycoprotein hormones alpha chain (CGA), which is the common alpha chain shared with LH, TSH, and hCG, and a unique beta chain, lutropin subunit beta (LHB), which confers specific binding to lutropin-choriogonadotropic hormone receptor (LHCGR).

Display_Name

Luteinizing Hormone

FULL_SYN

LH

Interstitial Cell-Stimulating Hormone

ICSH

Luteinizing Hormone

Lutropin

label

Luteinizing Hormone

NCI_META_CUI

CL1799696

Preferred_Name

Luteinizing Hormone

prefixIRI

Thesaurus:C190789

prefLabel

Luteinizing Hormone

Semantic_Type

Hormone

Amino Acid, Peptide, or Protein

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2273

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