loading...| Preferred Name |
Interferon Alfa-N1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2220 |
| Accepted_Therapeutic_Use_For |
Chronic Hepatitis C |
| CAS_Registry |
308067-63-2 |
| code |
C2220 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 |
| Contributing_Source |
GDC FDA |
| DEFINITION |
A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) |
| FDA_UNII_Code |
41697D4Z5C |
| FULL_SYN |
INTERFERON ALFA-N1 Interferon Alfa-N1 Humoferon Interferon Alfa Wellferon |
| Is_Value_For_GDC_Property | |
| label |
Interferon Alfa-N1 |
| Legacy Concept Name |
Interferon_Alfa-N1 |
| Maps_To |
Interferon Alfa-N1 |
| Preferred_Name |
Interferon Alfa-N1 |
| prefixIRI |
Thesaurus:C2220 |
| prefLabel |
Interferon Alfa-N1 |
| Semantic_Type |
Pharmacologic Substance Amino Acid, Peptide, or Protein |
| UMLS_CUI |
C0699817 |
| subClassOf |