loading...| Preferred Name |
Prasterone |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2265 |
| Accepted_Therapeutic_Use_For |
Adrenal insufficiency, replacement; Systemic lupus erythematosus, treatment and steroid treatment reduction |
| ALT_DEFINITION |
A substance being studied in the prevention of cancer. It is a type of steroid. |
| CAS_Registry |
53-43-0 |
| CHEBI_ID |
CHEBI:28689 |
| Chemical_Formula |
C19H28O2 |
| code |
C2265 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04) |
| Display_Name |
Prasterone |
| FDA_UNII_Code |
459AG36T1B |
| FULL_SYN |
17-Hormoforin Fidelin PRASTERONE Prasterone Dehydroisoandrosterone Diandron GL701 Therapeutic Dehydroepiandrosterone 5,6-Dehydroisoandrosterone dehydroepiandrosterone Dehydroepiandrosterone DHEA 3beta-Hydroxyandrost-5-en-17-one |
| Has_Salt_Form | |
| label |
Prasterone |
| Legacy Concept Name |
Therapeutic_Dehydroepiandrosterone |
| NCI_Drug_Dictionary_ID |
42419 |
| NSC Number |
9896 |
| PDQ_Closed_Trial_Search_ID |
42419 |
| PDQ_Open_Trial_Search_ID |
42419 |
| Preferred_Name |
Prasterone |
| prefixIRI |
Thesaurus:C2265 |
| prefLabel |
Prasterone |
| Semantic_Type |
Pharmacologic Substance Organic Chemical |
| UMLS_CUI |
C0011185 |
| subClassOf |