loading...| Preferred Name |
Mitogen-Activated Protein Kinase 9 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26379 |
| code |
C26379 |
| DEFINITION |
Mitogen-activated protein kinase 9 (424 aa, ~48 kDa) is encoded by the human MAPK9 gene. This protein is involved in cytokine signaling, protein phosphorylation and transcriptional regulation. |
| DesignNote |
MAPK9 mediates immediate-early gene expression. MAPK9 binds scaffolding proteins MAPK8IP1/2/3. MAPK9/UV-induced apoptosis appears related to cytochrome c-mediated cell death. Increased p53 stability in nonstressed cells results from MAPK9 blocked p53 ubiquitination. MAPK9 appears required for T-helper cell differentiation into Th1 cells. |
| FULL_SYN |
Mitogen-Activated Protein Kinase 9 MAPK 9 MAP Kinase 9 SAPK1a EC 2.7.11.24 Jun Kinase Stress-Activated Protein Kinase 1a Stress-Activated Protein Kinase JNK2 C-Jun Kinase 2 MAPK9 JNK-55 C-Jun N-Terminal Kinase 2 |
| label |
Mitogen-Activated Protein Kinase 9 |
| Legacy Concept Name |
MAP-Kinase-9 |
| OMIM_Number |
602896 |
| Preferred_Name |
Mitogen-Activated Protein Kinase 9 |
| prefixIRI |
Thesaurus:C26379 |
| prefLabel |
Mitogen-Activated Protein Kinase 9 |
| Semantic_Type |
Enzyme Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P45984 |
| UMLS_CUI |
C0290928 |
| subClassOf |