loading...| Preferred Name |
Cefdinir |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28914 |
| CAS_Registry |
91832-40-5 |
| CHEBI_ID |
CHEBI:3485 |
| Chemical_Formula |
C14H13N5O5S2 |
| code |
C28914 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation. |
| FDA_UNII_Code |
CI0FAO63WC |
| FULL_SYN |
Cefdinir CEFDINIR |
| label |
Cefdinir |
| Legacy Concept Name |
Cefdinir |
| Preferred_Name |
Cefdinir |
| prefixIRI |
Thesaurus:C28914 |
| prefLabel |
Cefdinir |
| Semantic_Type |
Pharmacologic Substance Organic Chemical Antibiotic |
| UMLS_CUI |
C0060405 |
| subClassOf |