loading...| Preferred Name |
Linezolid |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29158 |
| CAS_Registry |
165800-03-3 |
| CHEBI_ID |
CHEBI:63607 |
| Chemical_Formula |
C16H20FN3O4 |
| code |
C29158 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. (NCI04) |
| Display_Name |
Linezolid |
| FDA_UNII_Code |
ISQ9I6J12J |
| FULL_SYN |
Linezolid Zyvox LINEZOLID |
| label |
Linezolid |
| Legacy Concept Name |
Linezolid |
| NCI_Drug_Dictionary_ID |
735710 |
| PDQ_Closed_Trial_Search_ID |
735710 |
| PDQ_Open_Trial_Search_ID |
735710 |
| Preferred_Name |
Linezolid |
| prefixIRI |
Thesaurus:C29158 |
| prefLabel |
Linezolid |
| Semantic_Type |
Pharmacologic Substance Organic Chemical Antibiotic |
| UMLS_CUI |
C0663241 |
| subClassOf |