Quercetin

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C792

A kaempferol with a hydroxyl group at C-3'.

117-39-5

CHEBI:16243

C15H10O7

C792

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

CRCH

CTRP

FDA

A polyphenolic flavonoid with potential chemopreventive activity. Quercetin, ubiquitous in plant food sources and a major bioflavonoid in the human diet, may produce antiproliferative effects resulting from the modulation of either EGFR or estrogen-receptor mediated signal transduction pathways. Although the mechanism of action of action is not fully known, the following effects have been described with this agent in vitro: decreased expression of mutant p53 protein and p21-ras oncogene, induction of cell cycle arrest at the G1 phase and inhibition of heat shock protein synthesis. This compound also demonstrates synergy and reversal of the multidrug resistance phenotype, when combined with chemotherapeutic drugs, in vitro. Quercetin also produces anti-inflammatory and anti-allergy effects mediated through the inhibition of the lipoxygenase and cyclooxygenase pathways, thereby preventing the production of pro-inflammatory mediators.

Quercetin

9IKM0I5T1E

2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one

3,3',4',5,7-Pentahydroxyflavone

Quercetin

2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one

QUERCETIN

C.I. Natural Yellow 10

Quercetin

Quercetin

43114

9219

43114

43114

Quercetin

Thesaurus:C792

Quercetin

Pharmacologic Substance

Organic Chemical

C0034392

mg

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68456