Preferred Name

Tavaborole

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81725

CAS_Registry

174671-46-6

Chemical_Formula

C7H6BFO2

code

C81725

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast. 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole inhibits fungal cytoplasmic leucyl-tRNA synthetase by preventing catalytic turnover, thus inhibiting synthesis of leucyl-tRNA(Leu) and consequentially blocking protein synthesis.

FDA_UNII_Code

K124A4EUQ3

FULL_SYN

TAVABOROLE

Tavaborole

AN2690

5-Fluoro-1,3-Dihydro-1-Hydroxy-2,1-Benzoxaborole

label

Tavaborole

Legacy Concept Name

_5-Fluoro-1_3-Dihydro-1-Hydroxy-2_1-Benzoxaborole

Preferred_Name

Tavaborole

prefixIRI

Thesaurus:C81725

prefLabel

Tavaborole

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C3642427

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28394

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C514

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http://purl.obolibrary.org/obo/CHEBI_77942 Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体 LOOM
http://purl.obolibrary.org/obo/CHEBI_77942 The Drug Ontology / 药物本体 LOOM
http://purl.bioontology.org/ontology/MESH/C512998 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bioontology.org/ontology/ATC/D01AE24 Anatomical Therapeutic Chemical Classification / 解剖学治疗学及化学分类系统 LOOM