loading...| Preferred Name |
Discoid lupus erythematosus |
| ID |
http://www.orpha.net/ORDO/Orphanet_90281 |
| definition |
A rare form of chronic cutaneous lupus erythematosus characterized by erythematous, scaly papules and plaques preferentially occurring on sun-exposed skin areas (scalp, face, and ears) and exhibiting follicular plugging, pigmentary changes, and central atrophy, scarring, and telangiectasia. Skin biopsy shows a perivascular and periadnexal lymphocytic infiltrate and involvement of the dermoepidermal junction with thickening of the basement membrane and vacuolar degeneration of the basal cells. A small percentage of patients may develop systemic lupus erythematosus. |
| definition_citation |
Orphanet |
| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=90281 |
| has_age_of_onset |
Adult Adolescent Elderly Childhood |
| hasDbXref |
MedDRA:10013072 MeSH:D008179 UMLS:C0024138 ICD-10:L93.0 ICD-11:EB51.0 |
| label |
Discoid lupus erythematosus |
| notation |
ORPHA:90281 |
| part_of | |
| prefixIRI |
ORDO:Orphanet_90281 |
| prefLabel |
Discoid lupus erythematosus |
| present_in |
Sweden AND has_annual_incidence_average_value : 3.2 AND has_annual_incidence_range : 1-9 / 100 000 United States AND has_annual_incidence_average_value : 3.56 AND has_annual_incidence_range : 1-9 / 100 000 |
| treeView | |
| subClassOf |