Preferred Name

myeloid suppressor cell

Definitions

Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis. An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive.

ID

http://purl.obolibrary.org/obo/CL_0000889

comment

Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis.

bearer of

http://purl.obolibrary.org/obo/PATO_0001501

capable of

http://purl.obolibrary.org/obo/GO_0050777

definition

An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive.

has plasma membrane part

http://purl.obolibrary.org/obo/PR_000001012

http://purl.obolibrary.org/obo/PR_000001006

in_subset

http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim

label

myeloid suppressor cell

prefixIRI

CL:0000889

prefLabel

myeloid suppressor cell

subClassOf

http://purl.obolibrary.org/obo/PR_000050567

http://purl.obolibrary.org/obo/CL_0000766

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http://purl.obolibrary.org/obo/CL_0000889 Uber Anatomy Ontology / 超级解剖学本体 LOOM
http://purl.obolibrary.org/obo/CL_0000889 Uber Anatomy Ontology / 超级解剖学本体 SAME_URI
http://purl.obolibrary.org/obo/CL_0000889 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/CL_0000889 Experimental Factor Ontology / 实验性因素本体 SAME_URI
http://purl.obolibrary.org/obo/CL_0000889 Cell Ontology / 细胞本体 LOOM
http://purl.obolibrary.org/obo/CL_0000889 Cell Ontology / 细胞本体 SAME_URI