loading...| Preferred Name |
apoptotic process |
| Synonyms |
apoptotic programmed cell death cell suicide signaling (initiator) caspase activity activation of apoptosis induction of apoptosis by p53 apoptosis induction of apoptosis type I programmed cell death apoptosis activator activity caspase-dependent programmed cell death apoptotic cell death apoptosis signaling cellular suicide commitment to apoptosis apoptotic program programmed cell death by apoptosis |
| Definitions |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| ID |
http://purl.obolibrary.org/obo/GO_0006915 |
| database_cross_reference |
Wikipedia:Apoptosis |
| definition |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| has_alternative_id |
GO:0008632 GO:0006917 |
| has_broad_synonym |
cell suicide cellular suicide |
| has_exact_synonym |
apoptotic programmed cell death apoptotic cell death programmed cell death by apoptosis |
| has_narrow_synonym |
activation of apoptosis apoptosis type I programmed cell death apoptosis signaling apoptotic program |
| has_obo_namespace |
biological_process |
| has_related_synonym |
signaling (initiator) caspase activity induction of apoptosis by p53 induction of apoptosis apoptosis activator activity caspase-dependent programmed cell death commitment to apoptosis |
| id |
GO:0006915 |
| label |
apoptotic process |
| never_in_taxon | |
| notation |
GO:0006915 |
| prefLabel |
apoptotic process |
| subClassOf |