Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

follicular dendritic cell

Definitions

A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451.

ID

http://purl.obolibrary.org/obo/CL_0000442

comment

Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451.

database_cross_reference

FMA:83037

MESH:D020566

BTO:0004267

definition

A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response.

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

label

follicular dendritic cell

prefixIRI

CL:0000442

prefLabel

follicular dendritic cell

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

subClassOf

http://purl.obolibrary.org/obo/CL_0000548

http://purl.obolibrary.org/obo/CL_0000473

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