| Preferred Name |
subcommissural organ |
| Synonyms |
dorsal subcommissural organ organum subcommissurale cerebral aqueduct subcommissural organ corpus subcommissurale SCO |
| Definitions |
Occurs throughout the vertebartes [PMID:9579598, DOI:10.1002/ar.1091260210]. First appears in hagfish(Olsson). In many species, including the human, it reaches its full development during embryonic life[PMID:9579598]. During the course of phyletic evolution, one notes various changes. Indeed, in lower vertebrates, the SCO presents a greater degree of enzyme activity than the ependyma while in birds the ependyma demonstrates a more intense activity than the SCO[PMID:479574] Sometimes preceded by flexural organ[DOI:10.1007/BF00303086]. Hypendymal cells are rare in non-mammals [PMID:9579598]. The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0002139 |
| comment |
Occurs throughout the vertebartes [PMID:9579598, DOI:10.1002/ar.1091260210]. First appears in hagfish(Olsson). In many species, including the human, it reaches its full development during embryonic life[PMID:9579598]. During the course of phyletic evolution, one notes various changes. Indeed, in lower vertebrates, the SCO presents a greater degree of enzyme activity than the ependyma while in birds the ependyma demonstrates a more intense activity than the SCO[PMID:479574] Sometimes preceded by flexural organ[DOI:10.1007/BF00303086]. Hypendymal cells are rare in non-mammals [PMID:9579598]. |
| database_cross_reference |
Wikipedia:Subcommissural_organ BIRNLEX:1028 CALOHA:TS-0986 UMLS:C0038533 DMBA:16514 GAID:794 BAMS:SCO BTO:0001820 TAO:0000683 EMAPA:35828 MA:0002941 DHBA:12101 HBA:9489 FMA:72414 MESH:D013351 SCTID:369193006 neuronames:483 ZFA:0000683 |
| definition |
The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]. |
| depicted by |
http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png |
| has part | |
| has_obo_namespace |
uberon |
| has_related_synonym |
dorsal subcommissural organ organum subcommissurale cerebral aqueduct subcommissural organ corpus subcommissurale SCO |
| IAO_0000232 |
Hypendymal cells being part of the subcommissural organ is not axiomatized as it is rare in non-mammals. Consider using GCIs if this axiom needs to be added. |
| id |
UBERON:0002139 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim |
| label |
subcommissural organ |
| notation |
UBERON:0002139 |
| part_of | |
| prefLabel |
subcommissural organ |
| present_in_taxon | |
| produces | |
| treeView | |
| subClassOf |