Preferred Name

base of crypt of Lieberkuhn

Synonyms

base part of epithelium of intestinal gland

basal portion of intestinal gland

base of intestinal gland

Definitions

The basal portion (further from lumen) of an intestinal crypt. Contains multipotent stem cells. Stem cells in the crypts divide to form daughter cells. One daughter cell from each stem cell division is retained as a stem cell. The other becomes committed to differentiate along one of four pathways to become an enterocyte, enteroendocrine cell, goblet cell or Paneth cell.

ID

http://purl.obolibrary.org/obo/UBERON_0013739

continuous with

http://purl.obolibrary.org/obo/UBERON_0013740

definition

The basal portion (further from lumen) of an intestinal crypt. Contains multipotent stem cells. Stem cells in the crypts divide to form daughter cells. One daughter cell from each stem cell division is retained as a stem cell. The other becomes committed to differentiate along one of four pathways to become an enterocyte, enteroendocrine cell, goblet cell or Paneth cell.

has exact synonym

base part of epithelium of intestinal gland

basal portion of intestinal gland

base of intestinal gland

has_obo_namespace

uberon

id

UBERON:0013739

label

base of crypt of Lieberkuhn

notation

UBERON:0013739

part_of

http://purl.obolibrary.org/obo/UBERON_0001983

prefLabel

base of crypt of Lieberkuhn

taxon_notes

Clearly defined prolifieration zones found in mammals. Not observed in agnathostomes, larval amphibians. Described in advanced species of fish and adult amphibians.

treeView

http://purl.obolibrary.org/obo/UBERON_0001983

subClassOf

http://purl.obolibrary.org/obo/UBERON_0011184

http://purl.obolibrary.org/obo/UBERON_0000483

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