vascular endothelial growth factor signaling pathway

VEGF signaling

VEGF-activated signaling pathway

vascular endothelial growth factor signalling pathway

The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.

http://purl.obolibrary.org/obo/GO_0038084

In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.

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2012-02-01T02:27:32Z

The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

VEGF signaling

VEGF-activated signaling pathway

vascular endothelial growth factor signalling pathway

biological_process

GO:0038084

vascular endothelial growth factor signaling pathway

GO:0038084

http://purl.obolibrary.org/obo/GO_0035924

vascular endothelial growth factor signaling pathway

http://purl.obolibrary.org/obo/GO_0035924

http://purl.obolibrary.org/obo/GO_0007169

http://purl.obolibrary.org/obo/GO_0007169