Medical Subject Headings / 医学主题词表

Last uploaded: September 7, 2023

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Preferred Name	Topotecan
Synonyms	NSC 609699
Definitions	An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
ID	http://purl.bioontology.org/ontology/MESH/D019772
altLabel	NSC 609699 Topotecan Hydrochloride SKF 104864 A 9-Dimethylaminomethyl-10-hydroxycamptothecin SK&F104864A SK&F 104864 A Hydrochloride, Topotecan Hycamtamine SKF-104864-A NSC609699 Hycamtin Hydrochloride, Nogitecan 9 Dimethylaminomethyl 10 hydroxycamptothecin Topotecan Monohydrochloride, (S)-Isomer SK&F-104864-A NSC-609699 Nogitecan Hydrochloride SKF104864A
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0700912 C0700913 C0700915 C0886549 C4082294 C0146224
DC	1
definition	An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
DX	19980101
HN	98; use TOPOTECAN (NM) 1991-97
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB	0 7M7YKX2N15 956S425ZCY
isa	http://purl.bioontology.org/ontology/MESH/D059004
LT	TRD
Machine permutation	98; TOPOTECAN was indexed under CAMPTOTHECIN/analogs & derivatives 1991-97
Mapped from	http://purl.bioontology.org/ontology/MESH/C410030 http://purl.bioontology.org/ontology/MESH/C419192 http://purl.bioontology.org/ontology/MESH/C512566 http://purl.bioontology.org/ontology/MESH/C434884 http://purl.bioontology.org/ontology/MESH/C427583 http://purl.bioontology.org/ontology/MESH/C419191 http://purl.bioontology.org/ontology/MESH/C410031 http://purl.bioontology.org/ontology/MESH/C475944 http://purl.bioontology.org/ontology/MESH/C496393 http://purl.bioontology.org/ontology/MESH/C105151 http://purl.bioontology.org/ontology/MESH/C419190
MDA	19970620
MMR	20170117
MN	D03.132.151.850
notation	D019772
PA	D059004
prefLabel	Topotecan
RR	123948-87-8 (Topotecan) 119413-54-6 (Topotecan Hydrochloride) 956S425ZCY
TERMUI	T058772 T058773 T058771 T529636 T058770 T058769 T058775 T359278 T058776 T058774
TH	FDA SRS (2014) NLM (1998) NLM (2004) USAN (1990) NLM (1999) INN (19XX)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D002166

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/LNC/LP172582-1	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	CUI
http://purl.bioontology.org/ontology/LNC/LP172582-1	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1413	National Cancer Institute Thesaurus / 美国国家癌症研究所词典	LOOM
http://purl.obolibrary.org/obo/CHEBI_63632	Chemical Entities of Biological Interest Ontology / 生物相关的化学实体本体	LOOM
http://purl.obolibrary.org/obo/CHEBI_63632	Experimental Factor Ontology / 实验性因素本体	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000022037	Ontology of Drug Adverse Events / 药物不良反应本体	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU046380	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	CUI
http://purl.bioontology.org/ontology/LNC/MTHU046380	Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码	LOOM
http://purl.bioontology.org/ontology/ATC/L01CE01	Anatomical Therapeutic Chemical Classification / 解剖学治疗学及化学分类系统	CUI
http://purl.bioontology.org/ontology/ATC/L01CE01	Anatomical Therapeutic Chemical Classification / 解剖学治疗学及化学分类系统	LOOM