| Preferred Name |
T-Cell Surface Glycoprotein CD5 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73124 |
| code |
C73124 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 |
| Contributing_Source |
CTRP GDC |
| DEFINITION |
T-cell surface glycoprotein CD5 (495 aa, ~54 kDa) is encoded by the human CD5 gene. This protein may be involved in regulating the proliferation of T-cells. |
| DesignNote |
T-cell surface glycoprotein CD5 is a membrane bound glycoprotein expressed on all mature T-cells, thymocytes, and a subset of mature B-cells. Antibodies that specifically bind to CD5 can enhance T-cell receptor-mediated T-cell activation. This protein can bind to CD72 antigen. (Abbas et al., Cellular and Molecular Immunology, 2d ed, p156) |
| Display_Name |
T-Cell Surface Glycoprotein CD5 |
| FULL_SYN |
Lymphocyte Antigen CD5 CD5 Antigen CD5 Lymphocyte Antigen T1/Leu-1 T-Cell Surface Glycoprotein CD5 |
| Is_Value_For_GDC_Property | |
| label |
T-Cell Surface Glycoprotein CD5 |
| Legacy Concept Name |
T-Cell_Surface_Glycoprotein_CD5 |
| Maps_To |
CD5 |
| OMIM_Number |
153340 |
| Preferred_Name |
T-Cell Surface Glycoprotein CD5 |
| prefixIRI |
Thesaurus:C73124 |
| prefLabel |
T-Cell Surface Glycoprotein CD5 |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
P06127 |
| UMLS_CUI |
C0054964 |
| subClassOf |