Preferred Name

chemical synaptic transmission

Synonyms

signal transmission across a synapse

synaptic transmission

neurotransmission

Definitions

The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.

ID

http://purl.obolibrary.org/obo/GO_0007268

database_cross_reference

Wikipedia:Neurotransmission

has_broad_synonym

signal transmission across a synapse

synaptic transmission

has_obo_namespace

biological_process

has_related_synonym

neurotransmission

id

GO:0007268

imported from

http://purl.obolibrary.org/obo/go.owl

in subset

http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_synapse

label

chemical synaptic transmission

notation

GO:0007268

prefLabel

chemical synaptic transmission

textual definition

The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.

has_participant

http://purl.obolibrary.org/obo/PR_P41145

http://purl.obolibrary.org/obo/PR_P50406

http://purl.obolibrary.org/obo/PR_P23975

http://purl.obolibrary.org/obo/PR_P08908

http://purl.obolibrary.org/obo/PR_Q05940

http://purl.obolibrary.org/obo/PR_P35372

http://purl.obolibrary.org/obo/PR_P28223

http://purl.obolibrary.org/obo/PR_P21918

http://purl.obolibrary.org/obo/PR_P41595

http://purl.obolibrary.org/obo/PR_P28335

http://purl.obolibrary.org/obo/PR_P34969

http://purl.obolibrary.org/obo/PR_P54219

http://purl.obolibrary.org/obo/PR_P31645

http://purl.obolibrary.org/obo/PR_O75311

http://purl.obolibrary.org/obo/PR_P41143

subClassOf

http://purl.obolibrary.org/obo/GO_0007267

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