loading...| Preferred Name |
progressive multifocal leukoencephalopathy |
| Synonyms |
PML |
| Definitions |
A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma. |
| ID |
http://purl.obolibrary.org/obo/DOID_643 |
| database_cross_reference |
ICD10CM:A81.2 NCI:C26815 UMLS_CUI:C0023524 MESH:D007968 ICD9CM:046.3 GARD:7468 SNOMEDCT_US_2022_09_01:22255007 |
| definition |
A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma. |
| has material basis in | |
| has symptom |
http://purl.obolibrary.org/obo/SYMP_0000605 http://purl.obolibrary.org/obo/SYMP_0000508 |
| has_obo_namespace |
disease_ontology |
| has_related_synonym |
PML |
| id |
DOID:643 |
| in_subset |
http://purl.obolibrary.org/obo/doid#DO_rare_slim http://purl.obolibrary.org/obo/doid#NCIthesaurus http://purl.obolibrary.org/obo/doid#DO_infectious_disease_slim |
| label |
progressive multifocal leukoencephalopathy |
| notation |
DOID:643 |
| prefLabel |
progressive multifocal leukoencephalopathy |
| subClassOf |