loading...| Preferred Name |
fibroblast |
| Definitions |
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. |
| ID |
http://purl.obolibrary.org/obo/CL_0000057 |
| comment |
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. 这些细胞可以是波形蛋白阳性，纤连蛋白阳性，fsp1阳性，MMP-1阳性，胶原I阳性，胶原III阳性和α-SMA阴性。 分泌富含胶原和其他大分子的细胞外基质的结缔组织细胞。 These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. 间充质来源的结缔组织细胞，分泌蛋白质，尤其是分子胶原蛋白，结缔组织的细胞外纤维状基质由其形成。 在结缔组织中发现的大而扁平的椭圆形细胞，负责纤维的形成。 A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. |
| database_cross_reference |
BTO:0000452 FMA:63877 CALOHA:TS-0362 VHOG:0001482 |
| definition source |
BTO:0000452 NIFSTD:nlx_cell_20090201 CL:0000057 |
| develops_from | |
| label |
fibroblast 成纤维细胞 |
| prefixIRI |
CL:0000057 |
| prefLabel |
fibroblast |
| seeAlso |
EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496 |
| textual definition |
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. 分泌富含胶原和其他大分子的细胞外基质的结缔组织细胞。有分支过程的轮廓扁平，不规则；呈梭形或纺锤形。 |
| treeView | |
| 引自 |
http://purl.obolibrary.org/obo/uberon.owl |
| 替代术语 |
primary dermal fibroblast 小鼠胚胎成纤维细胞 mouse embryonic fibroblast 原发性真皮成纤维细胞 |
| 有_obo_命名空间 |
细胞 cell |
| 术语编辑者 |
James Malone Tomasz Adamusiak |
| subClassOf |