loading...| Preferred Name |
vasculitis |
| Synonyms |
angiitis systemic vasculitis |
| Definitions |
Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. BehC'et disease) to relatively minor skin disease. |
| ID |
http://purl.obolibrary.org/obo/MONDO_0018882 |
| closeMatch | |
| database_cross_reference |
EFO:0006803 SCTID:31996006 MESH:D014657 MedDRA:10036023 NCIT:C26912 DOID:865 UMLS:C0042384 GARD:0009565 Orphanet:52759 MedDRA:10047115 Wikipedia:Vasculitis Orphanet:280369 |
| definition |
Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. BehC'et disease) to relatively minor skin disease. |
| exactMatch |
http://identifiers.org/mesh/D014657 http://identifiers.org/snomedct/31996006 http://purl.obolibrary.org/obo/NCIT_C26912 http://linkedlifedata.com/resource/umls/id/C0042384 |
| has characteristic | |
| has_narrow_synonym |
systemic vasculitis |
| has_related_synonym |
angiitis |
| id |
MONDO:0018882 |
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_group_of_disorders |
| label |
vasculitis |
| narrowMatch | |
| notation |
MONDO:0018882 |
| prefLabel |
vasculitis |
| treeView | |
| subClassOf |