loading...| Preferred Name |
Alzheimer Disease |
| Synonyms |
Alzheimer Disease, Late Onset |
| Definitions |
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
| ID |
http://purl.bioontology.org/ontology/MESH/D000544 |
| altLabel |
Alzheimer Disease, Late Onset Alzheimer Dementias Alzheimer Syndrome Early Onset Alzheimer Disease Alzheimer Disease, Familial (FAD) Alzheimer's Disease, Focal Onset Primary Senile Degenerative Dementia Alzheimer's Disease Alzheimer Type Senile Dementia Dementia, Alzheimer-Type (ATD) Alzheimer Dementia Senile Dementia Alzheimer Sclerosis Familial Alzheimer Disease (FAD) Senile Dementia, Acute Confusional Familial Alzheimer Diseases (FAD) Alzheimers Diseases Late Onset Alzheimer Disease Presenile Dementia Acute Confusional Senile Dementia Sclerosis, Alzheimer Alzheimer Type Dementia (ATD) Alzheimer Disease, Early Onset Alzheimer's Diseases Dementia, Alzheimer Alzheimer Type Dementia Senile Dementia, Alzheimer Type Alzheimer-Type Dementia (ATD) Dementia, Alzheimer Type Dementia, Senile Alzheimer Diseases Presenile Alzheimer Dementia Dementia, Primary Senile Degenerative Dementia, Presenile Focal Onset Alzheimer's Disease |
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
| cui |
C0750900 C0494463 C0276496 C0546126 C0011265 C0750901 C0002395 |
| DC |
1 |
| definition |
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
| DX |
19840101 |
| FX |
D016875 D016900 D016657 D016229 D020232 D016564 D018888 |
| HN |
1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D016229 http://purl.bioontology.org/ontology/MESH/D020232 http://purl.bioontology.org/ontology/MESH/D016875 http://purl.bioontology.org/ontology/MESH/D016657 http://purl.bioontology.org/ontology/MESH/D016900 |
| Machine permutation |
1998; see ALZHEIMER'S DISEASE 1984-1997, see DEMENTIA, PRESENILE 1967-1983, see PSYCHOSES, PRESENILE 1963-1966; for DEMENTIA PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE, SENILE see DEMENTIA 1981-1999; for DEMENTIA, SENILE see DEMENTIA 1966-1999 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C536599 http://purl.bioontology.org/ontology/MESH/C565728 http://purl.bioontology.org/ontology/MESH/C564330 http://purl.bioontology.org/ontology/MESH/C536596 http://purl.bioontology.org/ontology/MESH/C564622 http://purl.bioontology.org/ontology/MESH/C566299 http://purl.bioontology.org/ontology/MESH/C564329 http://purl.bioontology.org/ontology/MESH/C536598 http://purl.bioontology.org/ontology/MESH/C563254 http://purl.bioontology.org/ontology/MESH/C536595 http://purl.bioontology.org/ontology/MESH/C565078 http://purl.bioontology.org/ontology/MESH/C565251 http://purl.bioontology.org/ontology/MESH/C566999 http://purl.bioontology.org/ontology/MESH/C567000 http://purl.bioontology.org/ontology/MESH/C567463 http://purl.bioontology.org/ontology/MESH/C565228 http://purl.bioontology.org/ontology/MESH/C566465 http://purl.bioontology.org/ontology/MESH/C567022 http://purl.bioontology.org/ontology/MESH/C536594 http://purl.bioontology.org/ontology/MESH/C565325 http://purl.bioontology.org/ontology/MESH/C566998 |
| MDA |
19990101 |
| MMR |
20200116 |
| MN |
C10.228.140.380.100 F03.615.400.100 C10.574.945.249 |
| notation |
D000544 |
| prefLabel |
Alzheimer Disease |
| TERMUI |
T365968 T365981 T001654 T010818 T365966 T366227 T369934 T365983 T843727 T010820 T840888 T000915952 T369933 T365965 T000998303 T840887 T365964 T366225 T001655 T843728 T365982 T366226 T365967 T366224 |
| TH |
NLM (1975) NLM (1998) NLM (2021) NLM (1967) NLM (2018) NLM (2000) NLM (1966) ORD (2010) OMIM (2013) GHR (2014) |
| tui |
T048 T047 |
| subClassOf |