Cell Ontology / 细胞本体

Last uploaded: September 7, 2023
Preferred Name

pericyte

Synonyms

cell of Rouget

pericyte cell

adventitial reticular cell

pericyte of Rouget

adventitial cell

ARC

Definitions

An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.

ID

http://purl.obolibrary.org/obo/CL_0000669

comment

Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A.

database_cross_reference

BTO:0002441

FMA:63174

definition

An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.

has_exact_synonym

cell of Rouget

pericyte cell

adventitial reticular cell

pericyte of Rouget

ARC

has_related_synonym

adventitial cell

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

label

pericyte

prefixIRI

CL:0000669

prefLabel

pericyte

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

subClassOf

http://purl.obolibrary.org/obo/CL_0008034

http://purl.obolibrary.org/obo/CL_0000183

http://purl.obolibrary.org/obo/CL_0000630

http://purl.obolibrary.org/obo/CL_0002320

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