Preferred Name

Sepsis

Definitions

<h3>What is sepsis?</h3> <p>Sepsis is your body's overactive and extreme response to an <a href="https://medlineplus.gov/infectiousdiseases.html">infection</a>. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.</p> <h3>What causes sepsis?</h3> <p>Sepsis happens when an infection you already have triggers a chain reaction throughout your body. <a href="https://medlineplus.gov/bacterialinfections.html">Bacterial infections</a> are the most common cause, but other types of infections can also cause it.</p> <p>The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an infection that develops after surgery. Sometimes, sepsis can occur in people who didn't even know that they had an infection.</p> <h3>Who is at risk for sepsis?</h3> <p>Anyone with an infection could get sepsis. But certain people are at higher risk:</p><ul> <li>Adults 65 or older</li> <li>People with chronic conditions, such as <a href="https://medlineplus.gov/diabetes.html">diabetes</a>, <a href="https://medlineplus.gov/lungdiseases.html">lung disease</a>, <a href="https://medlineplus.gov/cancer.html">cancer</a>, and <a href="https://medlineplus.gov/kidneydiseases.html">kidney disease</a></li> <li>People with weakened immune systems</li> <li>Pregnant women</li> <li>Children younger than one</li> </ul> <h3>What are the symptoms of sepsis?</h3> <p>Sepsis can cause one or more of these symptoms:</p><ul> <li>Rapid breathing and heart rate</li> <li><a href="https://medlineplus.gov/breathingproblems.html">Shortness of breath</a></li> <li>Confusion or disorientation</li> <li>Extreme pain or discomfort</li> <li><a href="https://medlineplus.gov/fever.html">Fever</a>, shivering, or feeling very cold</li> <li>Clammy or sweaty skin</li> </ul> <p>It's important to get medical care <strong>right away</strong> if you think you might have sepsis or if your infection is not getting better or is getting worse.</p> <h3>What other problems can sepsis cause?</h3> <p>Severe cases of sepsis can lead to septic shock, where your blood pressure drops to a dangerous level and multiple organs can fail.</p> <h3>How is sepsis diagnosed?</h3> <p>Your health care provider may use many tools to make a diagnosis:</p><ul> <li>A medical history, which includes asking about your symptoms </li> <li>A physical exam, including checking <a href="https://medlineplus.gov/vitalsigns.html">vital signs</a> (your temperature, blood pressure, heart rate, and breathing)</li> <li>Lab tests that check for signs of infection or organ damage</li> <li><a href="https://medlineplus.gov/diagnosticimaging.html">Imaging tests</a> such as an <a href="https://medlineplus.gov/xrays.html">x-ray</a> or a <a href="https://medlineplus.gov/ctscans.html">CT scan</a> to find the location of the infection</li> </ul> <p>Many of the signs and symptoms of sepsis can also be caused by other medical conditions. This may make sepsis hard to diagnose in its early stages.</p> <h3>What are the treatments for sepsis?</h3> <p>It is very important to get treatment right away. Treatment usually includes:</p><ul> <li><a href="https://medlineplus.gov/antibiotics.html">Antibiotics</a></li> <li>Maintaining blood flow to organs. This may involve getting <a href="https://medlineplus.gov/oxygentherapy.html">oxygen</a> and intravenous (IV) fluids.</li> <li>Treating the source of the infection</li> <li>If needed, medicines to increase blood pressure</li> </ul> <p>In serious cases, you might need kidney dialysis or a breathing tube. Some people need surgery to remove tissue damaged by the infection.</p> <h3>Can sepsis be prevented?</h3> <p>To prevent sepsis, you should try to prevent getting an infection:</p><ul> <li>Take good care of any chronic health conditions that you have</li> <li>Get recommended <a href="https://medlineplus.gov/vaccines.html">vaccines</a></li> <li>Practice <a href="https://medlineplus.gov/germsandhygiene.html">good hygiene</a>, such as handwashing</li> <li>Keep cuts clean and covered until healed</li> </ul> <p class="">NIH: National Institute of General Medical SciencesCenters for Disease Control and Prevention</p>

ID

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0243026

cui

C0243026

Date created

06/03/2003

definition

What is sepsis?

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

What causes sepsis?

Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Bacterial infections are the most common cause, but other types of infections can also cause it.

The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an infection that develops after surgery. Sometimes, sepsis can occur in people who didn't even know that they had an infection.

Who is at risk for sepsis?

Anyone with an infection could get sepsis. But certain people are at higher risk:

What are the symptoms of sepsis?

Sepsis can cause one or more of these symptoms:

  • Rapid breathing and heart rate
  • Shortness of breath
  • Confusion or disorientation
  • Extreme pain or discomfort
  • Fever, shivering, or feeling very cold
  • Clammy or sweaty skin

It's important to get medical care right away if you think you might have sepsis or if your infection is not getting better or is getting worse.

What other problems can sepsis cause?

Severe cases of sepsis can lead to septic shock, where your blood pressure drops to a dangerous level and multiple organs can fail.

How is sepsis diagnosed?

Your health care provider may use many tools to make a diagnosis:

  • A medical history, which includes asking about your symptoms
  • A physical exam, including checking vital signs (your temperature, blood pressure, heart rate, and breathing)
  • Lab tests that check for signs of infection or organ damage
  • Imaging tests such as an x-ray or a CT scan to find the location of the infection

Many of the signs and symptoms of sepsis can also be caused by other medical conditions. This may make sepsis hard to diagnose in its early stages.

What are the treatments for sepsis?

It is very important to get treatment right away. Treatment usually includes:

  • Antibiotics
  • Maintaining blood flow to organs. This may involve getting oxygen and intravenous (IV) fluids.
  • Treating the source of the infection
  • If needed, medicines to increase blood pressure

In serious cases, you might need kidney dialysis or a breathing tube. Some people need surgery to remove tissue damaged by the infection.

Can sepsis be prevented?

To prevent sepsis, you should try to prevent getting an infection:

  • Take good care of any chronic health conditions that you have
  • Get recommended vaccines
  • Practice good hygiene, such as handwashing
  • Keep cuts clean and covered until healed

NIH: National Institute of General Medical SciencesCenters for Disease Control and Prevention

Inverse of RQ

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0600327

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0004610

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036983

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036690

Mapped from

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0243026

Mapped to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0243026

MP OTHER LANGUAGE URL

Spanish https://medlineplus.gov/spanish/sepsis.html

MP PRIMARY INSTITUTE URL

National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov/

notation

C0243026

prefLabel

Sepsis

Related to

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0004623

http://purl.bioontology.org/ontology/MEDLINEPLUS/C0032269

Scope Statement

Sepsis is a serious illness and can lead to a life threatening condition called septic shock. Read about symptoms, treatment and risk factors for sepsis.https://medlineplus.gov/sepsis.html

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MEDLINEPLUS/C3714514

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/MTHU010579 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.obolibrary.org/obo/HP_0100806 Experimental Factor Ontology / 实验性因素本体 LOOM
http://purl.obolibrary.org/obo/HP_0100806 Human Phenotype Ontology / 人类表型本体 LOOM
http://purl.obolibrary.org/obo/HP_0100806 GenEpiO / 基因组流行病学本体 LOOM
http://purl.obolibrary.org/obo/IDO_0000636 GenEpiO / 基因组流行病学本体 LOOM
http://purl.bioontology.org/ontology/LNC/LA10591-8 Logical Observation Identifier Names and Codes / 逻辑观察标识符名称和代码 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU055817 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 CUI
http://purl.bioontology.org/ontology/OMIM/MTHU055817 Online Mendelian Inheritance in Man / 在线人类孟德尔遗传数据库 LOOM
http://purl.bioontology.org/ontology/NCBITAXON/137507 National Center for Biotechnology Information (NCBI) Organismal Classification / 美国国家生物技术信息中心(NCBI)生物分类 LOOM
http://purl.bioontology.org/ontology/MESH/D018805 Medical Subject Headings / 医学主题词表 CUI
http://purl.bioontology.org/ontology/MESH/D018805 Medical Subject Headings / 医学主题词表 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/L1-1G4 《国际疾病分类》第11版中文版 / International Classification of Diseases, 11th Edition, China LOOM