loading...| Preferred Name |
Bulbar Palsy, Progressive |
| Synonyms |
Progressive Bulbar Palsies |
| Definitions |
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900) |
| ID |
http://purl.bioontology.org/ontology/MESH/D010244 |
| altLabel |
Progressive Bulbar Palsies Fazio Londe Disease Palsy, Bulbar Palsy, Progressive Bulbar Fazio Londe Syndrome Disease, Fazio-Londe's Bulbar Paralyses Bulbar Palsy Fazio Londe's Syndrome Progressive Bulbar Palsy of Childhood Fazio-Londe Disease Childhood Progressive Bulbar Palsy Fazio-Londe Syndrome Bulbar Palsies Syndrome, Fazio-Londe Bulbar Paralysis Syndrome, Fazio-Londe's Bulbar Palsy, Progressive, Of Childhood Palsies, Progressive Bulbar Fazio-Londe's Syndrome Fazio-Londe's Disease Disease, Fazio-Londe Bulbar Palsies, Progressive Paralysis, Bulbar Palsies, Bulbar Fazio Londe's Disease |
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
| cui |
C4082299 C0393540 C0030442 |
| DC |
1 |
| definition |
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900) |
| DX |
20000101 |
| HN |
2000(1966) |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Machine permutation |
2000; see PARALYSIS, BULBAR 1966-1999 |
| Mapped from | |
| MDA |
19990101 |
| MMR |
20220714 |
| MN |
C10.574.562.300 C10.668.467.300 |
| notation |
D010244 |
| prefLabel |
Bulbar Palsy, Progressive |
| TERMUI |
T001115762 T812345 T001115763 T030274 T372095 T372094 T001114240 T030275 T001114241 T365782 |
| TH |
NLM (2023) UNK (19XX) NLM (2000) NLM (1966) OMIM (2013) |
| tui |
T047 |
| subClassOf |