loading...| Preferred Name |
Motor Neuron Disease |
| Synonyms |
Motor System Disease |
| Definitions |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) |
| ID |
http://purl.bioontology.org/ontology/MESH/D016472 |
| altLabel |
Motor System Disease Scleroses, Lateral Lateral Scleroses, Primary Sclerosis, Lateral Neuron Diseases, Motor Motor System Diseases Motor Neuron Disease, Upper Primary Lateral Scleroses Neuron Disease, Motor Secondary Motor Neuron Disease Lateral Sclerosis Primary Lateral Sclerosis Lower Motor Neuron Disease Familial Motor Neuron Disease Anterior Horn Cell Disease Upper Motor Neuron Disease Motor Neuron Disease, Lower Motor Neuron Diseases Scleroses, Primary Lateral Sclerosis, Primary Lateral Motor Neuron Disease, Secondary Lateral Sclerosis, Primary Motor Neuron Disease, Familial Lateral Scleroses |
| AN |
general or unspecified; prefer specifics |
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
| cui |
C0154681 C0521659 C0085084 C0543858 C0270763 C0154682 C0270764 |
| DC |
1 |
| definition |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) |
| DX |
19920101 |
| HN |
92 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Inverse of RO | |
| Machine permutation |
92 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C567502 http://purl.bioontology.org/ontology/MESH/C563517 http://purl.bioontology.org/ontology/MESH/C536416 |
| MDA |
19910621 |
| MMR |
20100625 |
| MN |
C10.574.562 C10.668.467 |
| notation |
D016472 |
| prefLabel |
Motor Neuron Disease |
| TERMUI |
T372127 T372118 T372123 T049287 T372125 T372129 T372130 T372117 T372119 T002093 T372124 T372128 T372126 |
| TH |
UNK (19XX) NLM (1992) NLM (2000) |
| tui |
T047 |
| subClassOf |