loading...| Preferred Name |
Parkinson Disease |
| Synonyms |
Lewy Body Parkinson Disease |
| Definitions |
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
| ID |
http://purl.bioontology.org/ontology/MESH/D010300 |
| altLabel |
Lewy Body Parkinson Disease Parkinson's Disease, Lewy Body Idiopathic Parkinson Disease Parkinsonism, Primary Parkinson Disease, Idiopathic Lewy Body Parkinson's Disease Parkinson's Disease Primary Parkinsonism Idiopathic Parkinson's Disease Paralysis Agitans Parkinson's Disease, Idiopathic |
| AN |
/chem ind = PARKINSON DISEASE, SECONDARY /chem ind |
| AQL |
BL CF CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
| cui |
C0030567 |
| DC |
1 |
| definition |
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
| DX |
19670101 |
| EC |
chemically induced:Parkinson Disease, Secondary/chemically induced |
| FX |
D016631 |
| HN |
1979(1963) |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000401 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000209 |
| Inverse of RO | |
| Machine permutation |
1979; see PARKINSONISM 1967-1978, see PARALYSIS AGITANS 1963-1966 |
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C567726 http://purl.bioontology.org/ontology/MESH/C564345 http://purl.bioontology.org/ontology/MESH/C567730 http://purl.bioontology.org/ontology/MESH/C566552 http://purl.bioontology.org/ontology/MESH/C564653 http://purl.bioontology.org/ontology/MESH/C565324 http://purl.bioontology.org/ontology/MESH/C566823 http://purl.bioontology.org/ontology/MESH/C565238 http://purl.bioontology.org/ontology/MESH/C564486 http://purl.bioontology.org/ontology/MESH/C537240 http://purl.bioontology.org/ontology/MESH/C565276 http://purl.bioontology.org/ontology/MESH/C565204 http://purl.bioontology.org/ontology/MESH/C562469 http://purl.bioontology.org/ontology/MESH/C537176 |
| MDA |
19990101 |
| MMR |
20190521 |
| MN |
C10.228.662.600.400 C10.574.928.750 C10.228.140.079.862.500 |
| notation |
D010300 |
| prefLabel |
Parkinson Disease |
| TERMUI |
T030418 T364509 T364507 T364512 T364508 T364510 T364506 T364511 T030420 T364505 T030419 |
| TH |
NLM (1967) UNK (19XX) NLM (1992) NLM (2000) OMIM (2013) GHR (2014) |
| tui |
T047 |
| subClassOf |