loading...| Preferred Name |
Clofazimine |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47456 |
| CAS_Registry |
2030-63-9 |
| CHEBI_ID |
CHEBI:3749 |
| code |
C47456 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 |
| Contributing_Source |
CTRP FDA |
| DEFINITION |
A phenazine dye with anti-mycobacterial and anti-inflammatory activities. The exact mechanism through which clofazimine exerts its effect is unknown. However, it binds preferentially to mycobacterial DNA, thereby inhibiting DNA replication and cell growth. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria. |
| Display_Name |
Clofazimine |
| FDA_UNII_Code |
D959AE5USF |
| FULL_SYN |
CLOFAZIMINE 2-Phenazinamine, 3,5-dihydro-N,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino)- Lamprene 3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine Clofazimine |
| label |
Clofazimine |
| Legacy Concept Name |
Clofazimine |
| NCI_Drug_Dictionary_ID |
811244 |
| NSC Number |
141046 |
| Preferred_Name |
Clofazimine |
| prefixIRI |
Thesaurus:C47456 |
| prefLabel |
Clofazimine |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0008996 |
| subClassOf |